Terminology
Association_test
| English | Chinese |
|---|---|
| additive model | 加性模型 |
| alternative allele (ALT) | 备择（替代）等位？ |
| conditional analysis | 条件分析 |
| dominant model (DOM) | 显性模型 |
| effect allele (EA) | 效应等位 |
| effect allele frequency (EAF) | 效应等位频率 |
| genetic model | 遗传模型 |
| genomic control (GC) | 基因组控制 |
| genomic inflation factor | 基因组膨胀因子 |
| LD score regresssion | LD分数回归 |
| lead variant | 领先变异？ |
| leave-one-chromosome-out | 染色体留一法 |
| linear mixed model (LMM) | 线性混合模型 |
| Manhattan plot | 曼哈顿图 |
| multiplicative model | 积性模型 |
| non-effect allele (NEA) | 非效应等位 |
| non-risk allele | 非危险(风险)等位 |
| odds ratio (OR) | 比值比 |
| other allele | 其他等位 |
| proximal contamination | 近端污染 |
| quantile-quantile plot (QQ plot) | 分位数-分位数图 |
| recessive model (REC) | 隐性模型 |
| reference allele (REF) | 参考等位 |
| regional plot | 区域图 |
| risk allele | 危险(风险)等位 |
| sentinel variant | 哨兵变异？ |
| whole genome regression | 全基因组回归 |
Basics
| English | Chinese |
|---|---|
| binary trait | 二分类性状 |
| Common disease common variant hypothesis (CDCV) | 常见病常见变异假说 |
| expression quantitative trait locus (eQTL) | 表达数量性状基因座 |
| genome-wide association study (GWAS) | 全基因组关联分析 |
| metabolite quantitative trait locus (mQTL) | 代谢物数量性状基因座 |
| molecular quantitative trait locus | 分子数量性状基因座 |
| personalized medicine | 个体化医疗 |
| protein quantitative trait locus (pQTL) | 蛋白数量性状基因座 |
| quantitative trait locus (QTL) | 数量性状基因座 |
Fine-mapping
| English | Chinese |
|---|---|
| fine-mapping | 精确定位 |
Genetics
| English | Chinese |
|---|---|
| genetic correlation | 遗传相关 |
Imputation
| English | Chinese |
|---|---|
| dosage | 剂量 |
| imputation | 插补 |
| phasing | 基因定相 |
Mendelian_randomization
| English | Chinese |
|---|---|
| instrumental variable (IV) | 工具变量 |
| leave-one-SNP-out | SNP留一法 |
| Mendelian randomization (MR) | 孟德尔随机化 |
Polygenic_score
| English | Chinese |
|---|---|
| polygenic risk score (PRS) | 多基因风险分数 |
| polygenic score (PGS) | 多基因分数 |