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Terminology

Annotation

English Chinese
annotation 注释
Combined Annotation Dependent Depletion (CADD) 组合注释依赖耗竭?
predicted loss-of-function (pLoF) 预测功能失去

Epigenetics

English Chinese
Assay of Transposase Accessible Chromatin sequencing (ATAC-seq) 染色质转座酶可及性测序
bisulfite sequencing (BS-seq) 重亚硫酸盐测序
Chromatin Immuno-Precipitation sequencing (ChIP-seq) 染色质免疫沉淀测序
chromosome conformation capture (3C) 染色体构象捕获
chromosome conformation capture carbon copy (5C) 染色体构象捕获碳拷贝
chromosome conformation capture-on-chip (4C) 染色体构象捕获芯片
circular chromosome conformation capture (4C) 环状染色体构象捕获
DNase I hypersensitive sites sequencing (DNase-seq) 脱氧核糖核酸酶I超敏位点测序
Formaldehyde-Assisted Isolation of Regulatory Elements sequencing (FAIRE-seq) 甲醛辅助分离调控元件测序
high-through chromosome conformation capture (Hi-C) 高通量染色体构象捕获
Micrococcal Nuclease sequencing (MNase-seq) 微球菌核酸酶测序
peak calling 峰值识别
reduced-representation bisulfite sequencing (RRBS) 简并代表性亚硫酸氢盐测序
single-cell Assay of Transposase Accessible Chromatin sequencing (scATAC-seq) 单细胞染色质转座酶可及性测序
single-cell reduced-representation bisulfite sequencing (scRRBS) 单细胞简并代表性亚硫酸氢盐测序
whole-genome bisulfite sequencing (WGBS) 全基因组重亚硫酸盐测序

Immune_cells

English Chinese
B cell receptor sequencing (BCR-Seq) B细胞受体测序
T cell receptor sequencing (TCR-Seq) 细胞受体测序

Long-read

English Chinese
high-fidelity sequencing (HiFi-seq) 高保真度测序
Nanopore sequencing 纳米孔测序
Single Molecule, Real-Time sequencing (SMRT-seq) 长读长单分子实时测序
single-cell sequencing protocol with improved read coverage across transcripts (SMART-seq) 提高转录本读取覆盖率的单细胞测序方案?

Omics

English Chinese
epigenome 表观基因组
epigenomics 表观基因组学
genome 基因组
genomics 基因组学
metagenome 宏基因组
metagenomics 宏基因组学
pangenome 泛基因组
pangenomics 泛基因组学
phenome 表型组
phenomics 表型组学
proteome 蛋白组
proteomics 蛋白组学
transcriptome 转录组
transcriptomics 转录组学

Sequencing

English Chinese
assembly 组装
base calling 碱基识别
contig 重叠组
DNA chip DNA芯片
DNA library DNA文库
DNA microarray DNA微阵列
genotype calling 基因型识别
long-read sequencing 长读长测序
next generation sequencing (NGS) 第二代测序
paired-end 双端
read 读序,读长
scaffold (基因)支架
sequence 序列
sequencing 测序
sequencing depth 测序深度
short-read sequencing 短读长测序
single-cell sequencing (sc-seq) 单细胞测序
single-end 单端
Third generation sequencing (TGS) 第三代测序
whole genome sequencing (WGS) 全基因组测序

Transcriptome

English Chinese
cap analysis gene expression sequencing (CAGE-seq) 帽分析基因表达测序?
single-cell RNA sequencing (scRNA-seq) 单细胞转录组测序
single-nucleus RNA-Seq (snRNA-seq) 单细胞核转录组测序
spatial transcriptomics 空间转录组
whole-genome bisulfite sequencing (RNA-seq) 全基因组亚硫酸氢盐测序